Well... Iran's been crotchety with just about everyone for several decades now, and the graphic novel is only about -- what, 10 years old.
That said, in my completely cynical opinion this is a pure excuse to get all outraged, indulge in some spin and public appearances, and generally make a stink about nothing.
THAT being said, the Persian empire back then was *huge* and is quite a fascinating subject for study, even if that's being used as an excuse today to get all pissy about .... a movie.
